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What is ACTOS?

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Trade name - ACTOS.

Active substance - PIOGLITAZONE.

Chemical formula - (RS)-5-(4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]BENZYL)THIAZOLIDINE-2,4-DIONE.

Pharmacological class - THIOZOLIDINEDIONE.

Therapeutic class - ANTIDIABETIC.

If you want to try medications from the THIOZOLIDINEDIONEs, you should buy ACTOS.

How ACTOS works?

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ACTOS is oral hypoglycemic agent, a derivative of THIOZOLIDINEDIONE series. You can buy ACTOS online without prescription if you need it. Medication is selective and powerful agonist of peroxisome proliferator-γ activated receptors (PPAR-γ). PPAR-γ receptors are found in muscle tissues, adipose tissues and liver tissues. Activation of PPAR-γ nuclear receptor modulates the transcription of several genes sensitive to insulin, which is involved in glucose and lipid metabolism control. ACTOS reduces insulin resistance in liver and peripheral tissues, thus the consumption of glucose and insulin increases and glucose production by the liver decreases. Unlike SULFONYLUREAS, ACTOS does not stimulate pancreas β-cells insulin secretion. You can buy ACTOS for type 2 diabetes treatment. In type 2 diabetes (insulin-dependent) reduction of insulin resistance leads to lower blood glucose levels, lower levels of plasma insulin and hemoglobin A1c (HbA1c, glycated hemoglobin) under the effect of ACTOS action. In type 2 diabetes (insulin dependent) with lipid disorders triglycerides level decreases and HDL cholesterol level increases during treatment with ACTOS. The level of total cholesterol and LDL in patients of this type doesn't change. If you have this type of diabetes, you should buy ACTOS.

Indications for ACTOS medical uses

ACTOS is used for type 2 diabetes mellitus (insulin-dependent) treatment. You can order and buy ACTOS in the online pharmacy.

Contraindications for ACTOS

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ACTOS cannot be used for diabetes mellitus type 1 (insulin-dependent) treatment, diabetic ketoacidosis treatment. Don't use ACTOS during pregnancy and lactation period, and in case of hypersensitivity to drug components. Consult your doctor if you want to buy ACTOS.

Precautions

Don't use ACTOS during pregnancy and lactation period. The drug can cause ovulation in patients with insulin resistance and anovulatory cycles in the period of treatment with THIAZOLIDINEDIONES, including ACTOS. This increases the risk of pregnancy if proper contraception hasn't been used. In experimental animal studies showed that ACTOS has no adverse effects on fertility and teratogenic effects. If you need to buy ACTOS you can do it online.

ACTOS interactions

Read attentively before you decide to buy ACTOS. During the usage of ACTOS and oral contraceptives the effectiveness of contraception may decrease. KETOCONAZOLE inhibits the metabolism of ACTOS in the liver in vitro.

Possible ACTOS side-effects

Metabolic side-effects: possible development of hypoglycemia (mild to severe). Side-effects from the hematopoietic system: possible anemia, decreased hemoglobin and hematocrit. Adverse reactions from the digestive system: seldom - increased level of AlAT. Before you buy ACTOS please consult a specialist.


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